Information : Persistent cellular motion control and trapping using mechanotactic signaling
نویسندگان
چکیده
FIG. S1. Influence of shear stress on cell directionality. (a) The polar histogram demonstrates distribution of angles of net migration vectors for a population of 100 cells; in the absence of any shearotactic signal (σ = 0 Pa) random cellular migration is observed. (b) Shear stress level of σ = 0.05 Pa with a population of 126 cells. Even at such exceptionally low shear stress level, we observe a noticeable directional bias in the direction of the shearotactic stimuli given by the red arrow. (c) Shear stress level of σ = 0.18 Pa with a population of 135 cells; a large majority of cells are heading in the direction of the mechanostimulus. (d) Shear stress level of σ = 0.30 Pa with a population of 129 cells. (e) Shear stress level of σ = 0.50 Pa with a population of 73 cells. In all polar histograms, 20 equally-spaced angular bins are considered.
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Persistent Cellular Motion Control and Trapping Using Mechanotactic Signaling
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